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Methods: Consented patients who undergo urogenital surgery and fail their post-operative voiding trial will be randomized to either extended release nitrofurantoin 100mg or an identical appearing placebo capsule to be taken daily while performing CISC and for three subsequent days after stopping CISC.

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Table III below illustrates comparison of the percent of unchanged drug recovered in the urine with commercially available nitrofurantoin macrocrystals in capsule form and nitrofurantoin tablets demonstrating a bioavailability of the drug utilizing the formulations of the present invention which is equivalent to or slightly greater than that of currently available nitrofurantoin capsules or tablets.

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