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What is the best tablet for migraine? Drugs That Stop Migraine Headaches Category Generic Name Brand Name Over-the-counter ibuprofen Advil, Motrin aspirin + acetaminophen + caffeine Excedrin Migraine, Excedrin, Goody's acetaminophen Excedrin Tension Headache, Tylenol, Valorin naproxen Aleve, Anaprox (prescription only), Naprosyn (prescription only) 9 more rows