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These tests will measure your blood levels of sure products from your liver and muscles. The results can help your physician find out if colchicine is inflicting damage to your liver or muscles. Colchicine oral tablet is used for long-term therapy of familial Mediterranean fever and prevention of gout flares. It comes with dangers when you don’t take it as prescribed. Research in animals has proven adverse results to the fetus when the mother takes the drug. colchicine What If colchicine I Miss A Dose? You will find a full record within the manufacturer's data leaflet provided along with your drugs. Speak colchicine with your doctor or pharmacist if any of the following proceed or turn into troublesome. There are a variety of way of life changes that you could make to assist scale back the chance of getting a gout assault. These embrace reducing weight , consuming a healthy diet and not drinking a lot alcohol or sugar-sweetened delicate drinks. Due to its long historic use in drugs, managed scientific trials have been small and there stays some caution with the usage of this drug in patients with co-morbidities.Colchicine is a widely used drug to deal with inflammatory diseases.Although total, antagonistic events have been numerically higher in patients with liver ailments, this risk was not significantly different from different disease indications.Furthermore, the sub-analysis excluding individuals with liver disease showed similar antagonistic events colchicine charges to the main analysis.Assessment methods included self-reporting of symptoms by sufferers, questioning of antagonistic occasions by investigators throughout research visits and endeavor blood exams and laboratory analyses.Methods used within the included studies to assess adverse occasions are described in Supplementary Table 1. colchicine colchicine colchicine Myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, pancytopenia, and aplastic anemiahave been reported with colchicine utilized in therapeutic doses. Colchicine is a substrate of the efflux transporter P-glycoprotein (P-gp), and the CYP3A4 metabolizing enzyme. Fatal drug interactions have been reported when colchicine is run with clarithromycin, a dual inhibitor of CYP3A4 and P-glycoprotein.