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Alzheimer's disease can no longer communicate, no longer recognizes family members especially his or her spouse, is unable to do anything for themselves, is totally reliant on others for all self-care and is no longer able to walk, then there seems little value in continue taking Alzheimer medications.
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It is recommended that a patient who is on a regimen of 10 mg twice daily of NAMENDA tablets be switched to NAMENDA XR 28 mg once-daily capsules the day following the last dose of a 10 mg NAMENDA tablet.
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The remaining dose is converted primarily to three polar metabolites: the N-gludantan conjugate, 6-hydroxy memantine and 1-nitroso-deaminated memantine.
As opposed to structural lesions and necrosis of the mammillary bodies, another study compared 9 patients with chronic Wernicke encephalopathy to 7 patients with Alzheimer disease and 37 controls.
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She had some confusion during the day but nothing compared to what she was like on 10 mg.
Aggression may also be a reaction to a person with dementia being unable to understand the world around them.
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Using a double blind design, where neither the investigators nor participants know who is receiving which treatment, participants will be randomly assigned to one of these four treatment groups (donepezil and memantine, memantine only, donepezil only or placebo).
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