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Diovan and Cozaar keep blood vessels from narrowing which improves blood flow and lowers blood pressure.

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Hydrochlorothiazide was not genotoxic in in vitro assays using strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 of Salmonella typhimurium (the Ames test); in the Chinese Hamster Ovary (CHO) test for chromosomal aberrations; or in in vivo assays using mouse germinal cell chromosomes, Chinese hamster bone marrow chromosomes, and the Drosophila sex-linked recessive lethal trait gene.

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If you become pregnant while taking triamterene and hydrochlorothiazide, call your doctor.

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The decision to use a combination as initial therapy should be individualized and should be shaped by considerations such as baseline blood pressure, the target goal, and the incremental likelihood of achieving goal with a combination compared to monotherapy.

If you become pregnant while taking lisinopril and hydrochlorothiazide, call your doctor immediately.

Your doctor may choose to stop this drug if your kidney problems get severe.

The safe use of triamterene and hydrochlorothiazide in pregnancy has not been established since there are no adequate and well-controlled studies with triamterene and hydrochlorothiazide in pregnant women.

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While most side effects do not require medical attention, you should notify your healthcare provider immediately if you experience any serious hydrochlorothiazide side effects such as seizures, unexplained swelling of the head and neck, or difficulty breathing.

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Peak (6 hour) effects were uniformly, but moderately larger than trough effects, with the trough to peak ratio for systolic and diastolic responses 50 to 95% and 60 to 90%, respectively.

The few instances of hepatic injury attributed to thiazide diuretics have been self-limited and rapidly reversed upon stopping the medication.

No significant drug-drug pharmacokinetic interactions have been found in interaction studies with hydrochlorothiazide, digoxin, warfarin, cimetidine and phenobarbital.

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Lisinopril is recommended for applying at: various hypertension's forms, diabetic nephropathy, as well as in combined therapy for early treatment of chronic heart failure and acute myocardial infarction.

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Although any chloride deficit is generally mild and usually does not require specific treatment except under extraordinary circumstances (as in liver disease or renal disease), chloride replacement may be required in the treatment of metabolic alkalosis.

Diovan (valsartan) is an angiotensin II receptor blocker (ARB) used for the treatment of high blood pressure or heart failure.

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US FDA pregnancy category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

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Side Effects List losartan-hydrochlorothiazide side effects by likelihood and severity.

This is because they have been associated with increased risk of new-onset diabetes and as such are recommended for use in patients over 65 where the risk of new-onset diabetes is outweighed by the benefits of controlling systolic blood pressure.

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Triamterene is commonly prepared in combination with for treatment of (high blood pressure) and (water retention).

If this edema produces discomfort, increased recumbency will often provide relief.

Unlike potassium sparing combination diuretic products, MICROZIDE may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.

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Papademetriou V, Price M, Notargiacomo A, Gottdiener J, Fletcher RD, Freis ED "Effect of diuretic therapy on ventricular arrhythmias in hypertensive patients with or without left ventricular hypertrophy.

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