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Why does levodopa become less effective?
Levodopa loses effectiveness over time. Often, higher and/or more frequent doses are required to control symptoms. However, this is mostly due to gradual worsening of the underlying disease rather than medication's effects diminishing. As long as you take it, levodopa will remain beneficial.
How long does it take for Parkinson's to progress?
While symptoms and disease progression are unique to each person, knowing the typical stages of Parkinson's can help you cope with changes as they occur. Some people experience the changes over 20 years or more. Others find the disease progresses more quickly.
What problems are avoided when carbidopa is given with levodopa?
Do not stop taking levodopa and carbidopa without talking to your doctor. If you suddenly stop taking levodopa and carbidopa, you could develop a serious syndrome that causes fever, rigid muscles, unusual body movements, and confusion. Your doctor will probably decrease your dose gradually.
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