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My best friend was diagnosed with breast cancer 6 years ago. Since that time her life has changed greatly, and she herself changed as well. It sounds ridiculous, but she became happier. I mean that she started cherishing every moment; she learnt how to value life and dear people. She is struggling with the disease but at the same time she lives every day as if it was the last day in her life. I think she's a very strong person and I hope she'll conquer the disease, she deserves it. Last year she was told her cancer spread to bones and this piece of news made her even stronger. Her doctor out her on Zometa and it brings vivid results: lowered pain, better blood tests. She is very satisfied with the way Zometa works for her bones. And according to her doctor the medication will help her better go through chemotherapy and achieve higher results. I pray for my friend every day and I recommend Zomets to other people for whom it might be useful.
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I dreaded the side-effects and had NONE. I had the intravenous infusion three days before Christmas 2011 and was scared that I would be flattened by the supposed side-effects like flu-like symptoms, bone ache and so forth and was pleasantly surprised. I am having my second one in just ten days time and hopefully it will be a repeat of the first one.
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In our New products review Steve Chaplin presents the clinical data relating to its efficacy and adverse effects, and Dr Elaine Dennison comments on its place in therapy.
After that I had many, many terrible side effects, some of which are still with me after a whole year.
Prolia uses monoclonal antibodies, so it works by an entirely different mechanism compared to Proclast and other medications.
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Finally, zolendronate may be used to treat the high blood calcium levels associated with certain types of cancers of the bone.
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She has been down there for a month and a half, and would like to come home again for a week then return to Florida.
Note: my doctor told me it can take 50 years to rid your body of the damage from Fosomax (or any of the other drugs in the same catagory).
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Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: Final results from CALGB trial 79809.
It is also used to prevent complications of cancer that has spread to the bone.
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For elderly patients with low bone mass, GIO, or osteoporosis who are at increased risk of fractures, bisphosphonates are first-line therapy (for women and men).
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Avoid having any type of dental surgery while you are being treated with zoledronic acid.
Reclast did not cause me any problems with med interaction.
At this point I do not trust the drug and feel that my Dr is not looking out for my best interest.
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We previously found no association between the use of anticonvulsant drugs and lower appendicular bone mass in this cohort, suggesting that the increased risk might be due to impairments of neuromuscular function we did not measure.
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The side effects listed are very frightening but I felt that the side effects of osteoporosis was worse as I am only 57and have already had a crush fracture in my spine and stress fracture in my foot.
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My opinion and a lot of others I have read on line, Prolia is a horrible drug.
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Call your doctor right away if you experience severe pain at any time during your treatment with zoledronic acid injection.
Pharmacokinetics not evaluated in patients with hepatic impairment; pharmacokinetics not affected by renal impairment.
While I do not share her beliefs, she is monitoring my progress as she has monitored me for more than 10 years.
At the other end of the scale, where high toxicity and dose bisphosphonates have been administered in patients suffering with malignancy, the jaws may have reached a 'state of no return'.
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For the analysis, expression of each gene was normalized to the housekeeping gene β-actin, F 5-GCACAGCTTCTTTGCAGCTCCTTCG-3, R 5-TTTGCACATGCCGGAGCCGTTG-3 generating a single value per biological replicate.
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In September 2011, the FDA updated the Reclast label to include additional information about its association with kidney failure.
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Drugs should be a last resort, not a first line of defense.
Calcitonin is indicated for patients who are approximately 5 years past menopause and have low bone mass, or with obvious osteoporosis, who choose not to or cannot take estrogen.
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Calcium Citrate and Vitamin D for about two weeks before my treatment and drank lots of water the day of the treatment before and after my treatment.
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Can the Save Our Bones Program help me?
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Had Novartis won and gotten its patent issued, it could not have prevented generics companies in India from continuing to sell generic Gleevec, but it could have obligated them to pay a reasonable royalty under a grandfather clause included in India's patent law.
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The study was designed by representatives of the sponsor, Novartis Pharma, in cooperation with the first author.
On October 1, 2007 the FDA announced plans to review the safety of bisphosphonate drugs used to treat osteoporosis in light of two studies published earlier this year in the New England Journal of Medicine.
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The active ingredient in ACLASTA is zoledronic acid.
This fact sheet is for men who would like to know more about bisphosphonates to relieve pain in prostate cancer that has spread to the bones.
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In general, the clinical studies have demonstrated mixed results on the efficacy of bisphosphonates and FD-related pain with small sample sizes and with most studies examining all skeletal regions, not just the craniofacial sites.
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